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A commonly used surrogate marker for the estimation of creatinine clearance is the Cockcroft–Gault (CG) formula, which in turn estimates GFR in ml/min: [21] It is named after the scientists, the asthmologist Donald William Cockcroft (b. 1946) and the nephrologist Matthew Henry Gault (1925–2003), who first published the formula in 1976, and ...
The above formula only applies for GFR calculation when it is equal to the clearance rate. The normal range of GFR, adjusted for body surface area , is 100–130 average 125 (mL/min)/(1.73 m 2 ) in men and 90–120 (mL/min)/(1.73 m 2 ) in women younger than the age of 40.
Carboplatin, sold under the brand name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer. [3] This includes ovarian cancer , lung cancer , head and neck cancer , brain cancer , and neuroblastoma . [ 3 ]
The NNH is an important measure in evidence-based medicine and helps physicians decide whether it is prudent to proceed with a particular treatment which may expose the patient to harms while providing therapeutic benefits.
John R. Cockcroft is Professor of Cardiology at the Heart Research Institute in Cardiff, Wales. Cockcroft also holds the position of Special Professor of Cardiovascular Disease Prevention at the University of Nottingham , and is currently visiting professor at Columbia Presbyterian Hospital in New York City .
Ernest Thomas Sinton Walton (6 October 1903 – 25 June 1995) was an Irish nuclear physicist and Nobel laureate in Physics who first split the atom. [1] He is best known for his work with John Cockcroft to construct one of the earliest types of particle accelerator, the Cockcroft–Walton generator.