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Febuxostat, sold under the brand name Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. [7] It is generally recommended only for people who cannot take allopurinol .
The price of a new drug (in most cases) is limited so that the cost of therapy with the new drug is in the range of the costs of therapy with existing drugs in the same therapeutic class. The price of a breakthrough drug is limited to the median of its prices in France, Germany, Italy, Sweden, Switzerland, Britain, and the United States.
Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid; thus, competitive inhibition can occur, and the presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used in ...
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Vadadustat, sold under the brand name Vafseo, is a medication used for the treatment of symptomatic anemia associated with chronic kidney disease. [2] [3] Vadadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor.
Reassuringly Expensive was the advertising slogan for Stella Artois in the United Kingdom from 1982 until 2007. The 1990s UK television advertising campaigns became known for their distinctive style of imitating European cinema and their leitmotif taken from the score of Jean de Florette , inspired, in turn, by Giuseppe Verdi 's La forza del ...
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Missy is a Holstein cow who was auctioned for $1.2 million in 2009, making her the most expensive cow in the world at that time.. Eastside Lewisdale Gold Missy is a twelve-year-old black and white Holstein cow from Canada that sold for 1.2 million dollars at the Morsan Road to the Royal Sale in Uxbridge, Ontario on Wednesday, November 11, 2009.