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Clarice and Lorenzo had ten children: Lucrezia de' Medici (Florence, 4 August 1470 – 15 November 1553); married Jacopo Salviati on 10 September 1486 and had 10 children, including Cardinal Giovanni Salviati, Cardinal Bernardo Salviati, Maria Salviati (mother of Cosimo I de' Medici, Grand Duke of Tuscany), and Francesca Salviati (mother of Pope Leo XI).
Lorenzo's grandfather, Cosimo de' Medici, was the first member of the Medici family to lead the Republic of Florence and run the Medici Bank simultaneously. As one of the wealthiest men in Europe, the elder Cosimo spent a very large portion of his fortune on government and philanthropy, for example as a patron of the arts and financier of public works. [7]
Contessina Antonia Romola di Lorenzo de' Medici (6 January 1478 – 29 June 1515) was an Italian noblewoman, ninthborn and fifth and last daughter of Lorenzo the Magnificent, Lord of Florence, and his wife Clarice Orsini. She was the wife of the Florentine Piero Ridolfi, later made Count Palatine by her elder brother Pope Leo X.
Lorenzo was born in Florence on 12 September 1492, a son of Piero di Lorenzo de' Medici and Alfonsina Orsini. [2] His paternal grandparents were Lorenzo the Magnificent and Clarice Orsini . [ 2 ] His maternal grandparents were Roberto Orsini , Count of Tagliacozzo and his wife, Catherine of San Severino .
A further source of friction between Lorenzo and Sixtus was the status of the archbishoprics of Florence, left vacant by the sudden death of Pietro Riario in January 1474; and of Pisa, left vacant by the death of Filippo de' Medici in October 1474. Lorenzo managed to obtain the archbishopric of Florence for his brother-in-law, Rinaldo Orsini ...
In 1478, he was one of the plotters behind the Pazzi conspiracy, a plan to assassinate the two most prominent members of the Medici family in Florence. In addition to conspiring, he was an intended beneficiary, once Lorenzo and Giuliano de' Medici had been killed. Riario would have become Lord of Florence. But the plot failed, as only Giuliano ...
Lucrezia de' Medici (14 February 1545 – 21 April 1561) was a member of the House of Medici and by marriage Duchess consort of Ferrara, Modena and Reggio from 1558 to 1561. Married to the intended husband of her elder sister Maria , who died young, her marriage was short and unhappy.
She had a good relationship with her daughter-in-law Lucrezia Tornabuoni, and she lived with her and her son Piero after her husband's death. [7] Her relationship with Piero's sons, Lorenzo di Piero di' Medici and Giuliano di Piero de' Medici, was close from their childhood and allowed her political influence as they became leaders. [8]