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The causes of acute kidney injury are commonly categorized into prerenal, intrinsic, and postrenal. Acute kidney injury occurs in up to 30% of patients following cardiac surgery. [23] Mortality increases by 60-80% in post-cardiopulmonary bypass patients who go on to require renal replacement therapy.
Prerenal acute kidney injury. Acute kidney injury, or AKI, is when the kidney isn’t functioning at 100% and that decrease in function usually over a few days. Actually, AKI used to be known as acute renal failure, or ARF, but AKI is a broader term that also includes subtle decreases in kidney function.
Renal azotemia (acute kidney failure) typically leads to uremia. It is an intrinsic disease of the kidney, generally the result of kidney parenchymal damage. Causes include kidney failure, glomerulonephritis, acute tubular necrosis, or other kidney disease. [3] The BUN:Cr in renal azotemia is less than 15.
Acute kidney injury (AKI), previously called acute renal failure (ARF), [12] [13] is a rapidly progressive loss of renal function, [14] generally characterized by oliguria (decreased urine production, quantified as less than 400 mL per day in adults, [15] less than 0.5 mL/kg/h in children or less than 1 mL/kg/h in infants); and fluid and ...
Kidney ischemia [1] is a disease with a high morbidity and mortality rate. [2] Blood vessels shrink and undergo apoptosis which results in poor blood flow in the kidneys. More complications happen when failure of the kidney functions result in toxicity in various parts of the body which may cause septic shock, hypovolemia, and a need for surgery. [3]
prerenal disease: the physiologic response to a decrease in kidney perfusion is an increase in sodium reabsorption to control hyponatremia, often caused by volume depletion or decrease in effective circulating volume (e.g. low output heart failure). above 2% [citation needed] or 3% [2] acute tubular necrosis or other kidney damage (postrenal ...
Normal or Postrenal (after the kidney) Normal range. Can also be postrenal disease. BUN reabsorption is within normal limits. <12:1 <40:1 Intrarenal (within kidney) Renal damage causes reduced reabsorption of BUN, therefore lowering the BUN:Cr ratio. Decreased ratio indicates liver disease (due to decreased urea formation) or malnutrition. [4]
Renal infarction is a medical condition caused by an abrupt disruption of the renal blood flow in either one of the segmental branches or the major ipsilateral renal artery. [3] Patients who have experienced an acute renal infarction usually report sudden onset flank pain , which is often accompanied by fever , nausea , and vomiting .