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Pigment gallstones are most commonly seen in the developing world. Risk factors for pigment stones include hemolytic anemias (such as from sickle-cell disease and hereditary spherocytosis), cirrhosis, and biliary tract infections. [30] People with erythropoietic protoporphyria (EPP) are at increased risk to develop gallstones.
Most people with gallstones do not have symptoms. [1] However, when a gallstone temporarily lodges in the cystic duct, they experience biliary colic. [1] Biliary colic is abdominal pain in the right upper quadrant or epigastric region. It is episodic, occurring after eating greasy or fatty foods, and leads to nausea and/or vomiting. [13]
The National Institute of Diabetes and Digestive and Kidney Diseases reports that 10 to 15 percent of the U.S. population, about 25 million people, are affected by gallstones. Your Guide to Gallstones
In the developed world, 10 to 15% of adults have gallstones. [3] Of those with gallstones, biliary colic occurs in 1 to 4% each year. [3] Nearly 30% of people have further problems related to gallstones in the year following an attack. [3] About 15% of people with biliary colic eventually develop inflammation of the gallbladder if not treated. [3]
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3D still showing gallstones. Gallstones form when the bile is saturated, usually with either cholesterol or bilirubin. [20] Most gallstones do not cause symptoms, with stones either remaining in the gallbladder or passed along the biliary system. [21] When symptoms occur, severe "colicky" pain in the upper right quadrant of the abdomen is often ...
Gallstones is a painful condition that affects approximately 20 per cent of Canadian women.
Although unusual, it is possible to have a common bile duct stone despite prior cholecystectomy. One study found that in patients diagnosed with choledocholithiasis, 28% had undergone prior cholecystectomy. Such stones are thought to be the result of stones missed at the time of the cholecystectomy, as opposed to the formation of new stones. [3]