Search results
Results From The WOW.Com Content Network
In science, ex vivo refers to experimentation or measurements done in or on tissue from an organism in an external environment with minimal alteration of natural conditions. [ 2 ] A primary advantage of using ex vivo tissues is the ability to perform tests or measurements that would otherwise not be possible or ethical in living subjects.
Mice are the most commonly used mammal species for live animal research. Such research is sometimes described as vivisection. Vivisection (from Latin vivus 'alive' and sectio 'cutting') is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure.
The terms animal testing, animal experimentation, animal research, in vivo testing, and vivisection have similar denotations but different connotations.Literally, "vivisection" means "live sectioning" of an animal, and historically referred only to experiments that involved the dissection of live animals.
This glossary of biology terms is a list of definitions of fundamental terms and concepts used in biology, the study of life and of living organisms.It is intended as introductory material for novices; for more specific and technical definitions from sub-disciplines and related fields, see Glossary of cell biology, Glossary of genetics, Glossary of evolutionary biology, Glossary of ecology ...
However, ex vivo gene therapies are better tolerated and less associated with severe immune responses. [63] The death of Jesse Gelsinger in a trial of an adenovirus -vectored treatment for ornithine transcarbamylase deficiency due to a systemic inflammatory reaction led to a temporary halt on gene therapy trials across the United States. [ 64 ]
Cell culture in a small Petri dish Epithelial cells in culture, stained for keratin (red) and DNA (green). Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment.
Advances in biology, genetics, computer science and robotics have given scientists new tools to help identify the root causes of human toxicity and disease." [ 81 ] People for the Ethical Treatment of Animals (PETA) in the US and UK: "We teamed up with CeeTox, Inc. to fund work on a new humane skin test that could replace painful tests on mice ...
Ex vivo lung perfusion, EVLP, is a form of machine perfusion aimed at sustaining the active aerobic cellular metabolism of donor lungs outside the donor's body prior to lung transplantation. This medical preservation technique typically occurs within a specialised machine engineered to mimic the conditions of the natural circulatory system .