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MRSA can be eradicated with a regimen of linezolid, [87] though treatment protocols vary and serum levels of antibiotics vary widely from person to person and may affect outcomes. [88] The effective treatment of MRSA with linezolid has been successful [87] in 87% of people. Linezolid is more effective in soft tissue infections than vancomycin.
Decolonization, also bacterial decolonization, is a medical intervention that attempts to rid a patient of an antimicrobial resistant pathogen, [1] such as methicillin-resistant Staphylococcus aureus (MRSA) or antifungal-resistant Candida. [2]
[72] [73] Various decolonization strategies have been used in hospitals in an effort to reduce transmission of bacteria and decrease overall infection rate. Decolonization effects are both directly and indirectly related via reduction of the overall bioburden when broadly administered within an acute care setting. There is the added benefit of ...
First-line treatment for serious invasive infections due to MRSA is currently glycopeptide antibiotics (vancomycin and teicoplanin). A number of problems with these antibiotics occur, such as the need for intravenous administration (no oral preparation is available), toxicity, and the need to monitor drug levels regularly by blood tests.
It is a potential treatment for methicillin-resistant Staphylococcus aureus (MRSA) and possibly Clostridioides difficile. It is being developed by Destiny Pharma Ltd. [2] [3] [4] Structurally, it is a dicationic porphyrin. [5] It has completed a phase I clinical trial for nasal decolonisation of MRSA—being tested against 5 bacterial strains.
Kerry L. LaPlante is an American pharmacist, academic and researcher. She is the Dean at the University of Rhode Island College of Pharmacy. She is a Professor of Pharmacy and former department Chair of the Department of Pharmacy Practice at the University of Rhode Island, an adjunct professor of medicine at Brown University, [1] an Infectious Diseases Pharmacotherapy Specialist, and the ...
Its role in therapy has been largely replaced by oxacillin (used for clinical antimicrobial susceptibility testing), flucloxacillin and dicloxacillin, but the term methicillin-resistant Staphylococcus aureus (MRSA) continues to be used to describe S. aureus strains resistant to all penicillins.
Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban .