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Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
Some genetic conditions that result in a "leucistic" appearance include piebaldism, Waardenburg syndrome, vitiligo, Chédiak–Higashi syndrome, flavism, isabellinism, xanthochromism, axanthism, amelanism, and melanophilin mutations. Pale patches of skin, feathers, or fur (often referred to as "depigmentation") can also result from injury.
Piebaldism is unrelated to conditions such as vitiligo or poliosis. Although "partial albinism" is a synonym for piebaldism, [ 3 ] it is a fundamentally different condition from true albinism . The vision problems associated with albinism are not usually present as eye pigmentation is normal.
Michael was diagnosed with vitiligo in 1983. The 13-time Grammy winner used fair-colored makeup and creams to cover the blotches, causing a very pale appearance. Michael first addressed the ...
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Although the overall frequency of disease-causing alleles does not vary much between populations, the practice of consanguineous marriage (marriage between second cousins or closer relatives) has been common in some Jewish communities, which produces a small increase in the number of children with congenital defects. [1]
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