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In the field of molecular biology, the ETS (E26 transformation-specific [2] or Erythroblast Transformation Specific [3]) family is one of the largest families of transcription factors and is unique to animals. There are 28 genes in humans, [4] 27 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila.
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. [6] The nuclear protein binds to a purine-rich sequence known as the PU-box found on enhancers of target genes, and regulates their expression in coordination with other transcription factors and cofactors.
ERG (ETS-related gene) is an oncogene. [ 5 ] [ 6 ] [ 7 ] ERG is a member of the ETS (erythroblast transformation-specific) family of transcription factors. [ 8 ] The ERG gene encodes for a protein, also called ERG, that functions as a transcriptional regulator.
ETS Like-1 protein Elk-1 is a protein that in humans is encoded by the ELK1. [5] Elk-1 functions as a transcription activator . It is classified as a ternary complex factor (TCF), a subclass of the ETS family , which is characterized by a common protein domain that regulates DNA binding to target sequences.
The human ETV6 protein is a member of the ETS transcription factor family; however, it more often acts to inhibit than stimulate transcription of its target genes.ETV6 protein contains 3 domains: a) the pointed N-terminal (i.e. PNT) domain which forms oligomer partners with itself as well as other transcription factors (e.g. FLI1) and is required for ETV6's transcriptional repressing activity ...
An orange-skinned, green-eyed alien princess, Starfire (real name Koriand'r) is formidable for her superhuman strength, faster-than-light flight, and ability to emit bright green energy bolts from either her hands or her eyes. Starfire is a generally happy and naive person and is relentlessly kind and polite to everyone, even to her occasional ...
With their “perfectly handsome sons” and “perfectly beautiful daughters,” as Lady Whistledown puts it, the family is the heart of the hit Netflix series “Bridgerton.”
13714 Ensembl ENSG00000158711 ENSMUSG00000026436 UniProt P28324 P41158 RefSeq (mRNA) NM_001973 NM_021795 NM_007923 NM_001376954 NM_001376955 NM_001376956 NM_001376957 NM_001376958 NM_001376959 RefSeq (protein) NP_001964 NP_068567 NP_068567.1 NP_031949 NP_001363883 NP_001363884 NP_001363885 NP_001363886 NP_001363887 NP_001363888 Location (UCSC) Chr 1: 205.6 – 205.63 Mb Chr 1: 131.94 – 131. ...