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Muscle pain and other symptoms often cause patients to stop taking a statin. [87] This is known as statin intolerance. A 2021 double-blind multiple crossover randomized controlled trial (RCT) in statin-intolerant patients found that adverse effects, including muscle pain, were similar between atorvastatin and placebo. [88]
These antibodies are known to also occur in people who do not take statin medications. [3] Conversely, these antibodies are absent in people who take statin medications but do not have myopathy. Thus, the presence of anti-HMG CoA reductase antibodies in someone who uses a statin and has myopathy strongly supports the diagnosis. [3]
Like all statins, rosuvastatin can possibly cause myopathy, rhabdomyolysis: [14] [4] muscle pain, tenderness, or weakness; lack of energy; fever; chest pain; jaundice: yellowing of the skin or eyes; dark colored, or foamy urine; pain in the upper right part of the abdomen; nausea; extreme tiredness; weakness; unusual bleeding or bruising; loss ...
Statins are generally recommended for adults between the ages of 40 and 75 who have heart disease risk factors. Despite having higher risks for cardiovascular disease, fewer older adults use statins.
[66] [67] [68] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the first year of treatment but can occur at any time during treatment. [66] Risk factors for statin induced rhabdomyolysis include older age, renal impairment, high dose statins and use of medications that reduce the breakdown ...
Aches and pains become more common in old age, which patients and doctors may mistakenly blame on the cholesterol-lowering drugs. Statins do not cause muscle pain, study suggests Skip to main content