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The FDA is also cautioning consumers about off-label use of quinine to treat leg cramps. [19] [20] Quinine is approved for treatment of malaria, but was also commonly prescribed to treat leg cramps and similar conditions. Because malaria is life-threatening, the risks associated with quinine use are considered acceptable when used to treat that ...
Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for malaria, as the bark contains quinine used to treat the disease. [1] The bark of several species of the genus Cinchona , family Rubiaceae indigenous to the western Andes of South America, was introduced to Jesuit missionaries during the 17th century ...
Cinchonism is a pathological condition caused by an overdose of quinine or its natural source, cinchona bark. Quinine and its derivatives are used medically to treat malaria and lupus erythematosus. In much smaller amounts, quinine is an ingredient of tonic drinks, acting as a bittering agent. Cinchonism can occur from therapeutic doses of ...
The quinine in tonic water will fluoresce under ultraviolet light. In fact, quinine will visibly fluoresce in direct sunlight against a dark background. [19] The quinine molecules release energy as light instead of heat, which is more common. The state is not stable, and the molecules will eventually return to a ground state and no longer glow ...
Among the quinoline alkaloids are the cinchona alkaloids quinine and quinidine, which are important due to their therapeutic potential, furthermore cinchonine and cinchonidine, as well as some furoquinoline alkaloids and acridine alkaloids.
Bark extracts had been used to treat malaria since at least 1632 and it was introduced to Spain as early as 1636 by Jesuit missionaries returning from the New World. It is on the World Health Organization's List of Essential Medicines. Treatment of malaria with quinine marks the first known use of a chemical compound to treat an infectious disease.
It is used as a treatment for chapped and irritated skin on humans and can be found in places such as drugstores, ski resorts, online vendors, and needlework stores, in addition to farm and feed stores. Its uses are claimed to be many, for example: "squeaky bed springs, psoriasis, dry facial skin, cracked fingers, burns, zits, diaper rash ...
Quinine is a quinuclidine derivative. Quinuclidine is structurally related to DABCO, in which the other bridgehead is also nitrogen, and to tropane, which has a slightly different carbon frame. Cinchona alkaloids, e.g. quinine, feature quinuclidine substituents. [7] Aceclidine, a simple quinuclidine derivative, is a drug used for treatment of ...