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If a persistent sore throat with signs of sepsis are found, physicians are cautioned to screen for Lemierre's syndrome. [15] Laboratory investigations reveal signs of a bacterial infection with elevated C-reactive protein, erythrocyte sedimentation rate and white blood cells (notably neutrophils). Platelet count can be low or high.
"Sepsis is an overwhelming body reaction for any infection and sepsis is a life-threatening condition," Rangaswamy said. "If not diagnosed early and not treated, it can cause significant mortality ...
The diagnosis is based on involvement of less than 10% of the skin. [2] It is known as TEN when more than 30% of the skin is involved and an intermediate form with 10 to 30% involvement. [3] A positive Nikolsky's sign is helpful in the diagnosis of SJS and TEN. [9] A skin biopsy is helpful, but not required, to establish a diagnosis of SJS and ...
Tonsillitis is inflammation of the tonsils in the upper part of the throat. It can be acute or chronic. [8] [9] [2] Acute tonsillitis typically has a rapid onset. [10] Symptoms may include sore throat, fever, enlargement of the tonsils, trouble swallowing, and enlarged lymph nodes around the neck. [1] [2] Complications include peritonsillar ...
F. necrophorum is responsible for 10% of acute sore throats, [4] 21% of recurrent sore throats [5] [6] and 23% of peritonsillar abscesses [7] with the remainder being caused by Group A streptococci or viruses.
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A progressively severe sore throat on one side and pain during swallowing (odynophagia) usually are the earliest symptoms. As the abscess develops, persistent pain in the peritonsillar area, fever , a general sense of feeling unwell , headache, and a distortion of vowels informally known as "hot potato voice" may appear.
The typical signs and symptoms of streptococcal pharyngitis are a sore throat, fever of greater than 38 °C (100 °F), tonsillar exudates (pus on the tonsils), and large cervical lymph nodes. [ 13 ] Other symptoms include: headache , nausea and vomiting , abdominal pain , [ 14 ] muscle pain , [ 15 ] or a scarlatiniform rash or palatal petechiae ...