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The brain requires approximately 3.3 ml of oxygen per 100 g of brain tissue per minute. Initially the body responds to lowered blood oxygen by redirecting blood to the brain and increasing cerebral blood flow. Blood flow may increase up to twice the normal flow but no more.
The most vulnerable cells in the brain, CA1 neurons of the hippocampus, are fatally injured by as little as 10 minutes without oxygen. However, the injured cells do not actually die until hours after resuscitation. [8] This delayed death can be prevented in vitro by a simple drug treatment even after 20 minutes without oxygen. [9]
You have a few MINUTES of oxygen in your body. Your life up to now has required hundreds of thousands of hours of routine heart beating and breathing to not-die - it's not something you can be ...
An abrupt stop of pulmonary gas exchange lasting for more than five minutes may permanently damage vital organs, especially the brain. Lack of oxygen to the brain causes loss of consciousness. Brain injury is likely if respiratory arrest goes untreated for more than three minutes, and death is almost certain if more than five minutes.
So, for 45 minutes, she was clinically dead.” “You can do the best CPR in the world, but if you don’t get enough blood to the brain, essentially they are alive but with brain damage,” he ...
The brain cannot survive long without oxygen, and the continued lack of oxygen in the blood, combined with the cardiac arrest, will lead to the deterioration of brain cells, causing first brain damage and eventually brain death after six minutes from which recovery is generally considered impossible. Hypothermia of the central nervous system ...