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Before delivery treatment of the mother with antibiotics reduces the rate of neonatal infection. [31] Prevention of the infection of the baby is done by treating the mother with penicillin. Since the adoption of this prophylactic treatment, infant mortality from GBS infection has decreased by 80%. [36]
Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
Children younger than five years old may have atypical presentations and many of the common signs and symptoms may be missing or different. Children younger than 3 years old can present with nasal congestion and a lower grade fever. [22] Infants may present with symptoms of increased irritability and decreased appetite. [22]
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The Centers for Disease Control and Prevention recommends treating symptomatic or babies born to an infected mother with unknown treatment status with procaine penicillin G, 50,000 U/kg dose IM a day in a single dose for 10 days. [34] Treatment for these babies can vary on a case-by-case basis.
This treatment is ineffective because it treats only the local ocular infection, whereas if it progresses to BPF, systemic antibiotic treatment is required. Although BPF is susceptible to many commonly used antibiotics, including ampicillin , cefuroxime , cefotaxime , rifampin , and chloramphenicol , by the time it is diagnosed the disease has ...