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Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [90] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [91] preeclampsia, [92] miscarriage, [93] seizures in children, [94] and many other adverse affects.
In addition, the augmentation of a selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor with lisdexamfetamine, a norepinephrine–dopamine releasing agent, recently failed to separate from placebo in phase III clinical trials of individuals with treatment-resistant depression, and clinical development was ...
Moclobemide is a benzamide, [13] derivative of morpholine, [98] which acts pharmacologically as a selective, reversible inhibitor of monoamine oxidase-A (RIMA), [10] a type of monoamine oxidase inhibitor (MAOI), and increases levels of norepinephrine (noradrenaline), dopamine, and especially serotonin [9] [99] in neuronal cells as well as in ...
Women are 4-5 times more likely to develop a clot during pregnancy and in the postpartum period than when they are not pregnant. [25] Hypercoagulability in pregnancy likely evolved to protect women from hemorrhage at the time of miscarriage or childbirth. In developing countries, the leading cause of maternal death is still hemorrhage. [25]
The data suggested that biological age increased by three per cent more per year in those who have been pregnant, and those with more than one pregnancy were said to age up to five months faster.
Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) [6] [7] [8] or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
New guidelines set by the American College of Obstetricians and Gynecologists emphasize that pregnancy risks should be characterized in five-year age groups—like ages 35–40, 40–44, et cetera ...
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