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The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Depression is commonly attributed to a deficiency in monoamines, such as serotonin. The monoamine hypothesis of depression suggests that depression is primarily caused by a deficiency of several monoamines, namely serotonin, dopamine and norepinephrine. [2] This hypothesis is widely accepted due to its simplicity. [3]
People low in dopamine use caffeine, sugar, alcohol, and illicit drugs to temporarily boost their dopamine levels. Serotonin depression is accompanied by anxiety and irritability. Dopamine-based ...
While depression is a complex condition with many factors involved, it is commonly attributed to an imbalance of several key monoamine neurotransmitters, including serotonin, dopamine and norepinephrine. This monoamine hypothesis of depression is popular because of the simplicity of the explanation. [4]
A 2020 review of studies published in the journal BMJ suggested an anti-inflammatory diet, meaning high in fiber, polyphenols, and unsaturated fatty acids, could help to reduce depressive symptoms ...
If you have low levels of dopamine, you might feel tired or unhappy, have low motivation, and could experience mood swings and concentration problems, the Cleveland Clinic says. High levels might ...