Search results
Results From The WOW.Com Content Network
H 2 receptor – Found mainly in the stomach lining (parietal cells), H2 receptors regulate gastric acid secretion by stimulating the production of hydrochloric acid. H2 antagonists (H2 blockers) are used to reduce stomach acid production and treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. [3]
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
3274 15466 Ensembl ENSG00000113749 ENSMUSG00000034987 UniProt P25021 P97292 RefSeq (mRNA) NM_001131055 NM_022304 NM_001367711 NM_001393460 NM_001393461 NM_001010973 NM_008286 RefSeq (protein) NP_001124527 NP_001354640 NP_001010973 Location (UCSC) Chr 5: 175.66 – 175.71 Mb Chr 13: 54.35 – 54.39 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse H 2 receptors are a type of histamine ...
Hydrochloric acid, also known as muriatic acid or spirits of salt, is an aqueous solution of hydrogen chloride (HCl). It is a colorless solution with a distinctive pungent smell. It is classified as a strong acid. It is a component of the gastric acid in the digestive systems of most animal species, including humans.
Bjerrum plot of speciation for a hypothetical monoprotic acid: AH concentration as a function of the difference between pK and pH. Carbonic acid is the formal Brønsted–Lowry conjugate acid of the bicarbonate anion, stable in alkaline solution. The protonation constants have been measured to great precision, but depend on overall ionic ...
The avian influenza is a disease previously known to primarily spread between birds and poultry, not other species. However, one specific subtype of bird flu called the H5N1 virus has crossed ...
The differences between the core canonical histones and their variants can be summarized as follows: (1) canonical histones are replication-dependent and are expressed during the S-phase of cell cycle whereas histone variants are replication-independent and are expressed during the whole cell cycle; (2) in animals, the genes encoding canonical ...
In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine). An alternative name is chlorhydrate, which comes from French. An archaic alternative name is muriate, derived from hydrochloric acid's ancient name: muriatic acid.