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[4] [5] Use is not recommended during pregnancy. [2] Xylometazoline is in the decongestant and alpha-adrenergic agonist families of medication. [5] [6] One study classified it with selectivity ratios in alpha 2 adrenergic receptors of 151 for a2A vs a2B, 4.5 a2A vs a2C, and 33.9 a2B vs a2C. Making it a highly selective a2A agonist. [7]
However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include: Oxymetazoline; Phenylephrine; Xylometazoline
Saline spray is a safe option for all adults and can be used as often as needed to relieve symptoms, but overuse may cause some of the fluid to drip from your nose. 2. Try nasal saline irrigation ...
He added that he hoped the research “will encourage use of hypertonic saline nose drops by healthcare professionals (3% hypertonic saline solutions are available) until an over-the-counter or ...
It appears to be safe in pregnancy and breastfeeding. [3] [9] Ipratropium is a short-acting muscarinic antagonist, [10] which works by causing smooth muscles to relax. [3] Common side effects of nasal spray may include headache, dry nose, dry mouth or throat, nasal or throat irritation, nosebleeds, bad taste in mouth, nausea, dizziness, or ...
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
The RSV vaccine, made by Pfizer, should only be given between 32 weeks and 36 weeks of pregnancy. The shot prompts the moms-to-be to develop virus-fighting antibodies that pass through the ...