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Spironolactone; Clinical data; Pronunciation / ˌ s p aɪ r oʊ n oʊ ˈ l æ k t oʊ n / SPY-roh-noh-LAK-tone, [1] / ˌ s p ɪər oʊ n oʊ ˈ l æ k t oʊ n / SPEER-oh-noh-LAK-tone [2] Trade names: Aldactone, others
Topical spironolactone is another prescription Dr. Spann recommends. Low-level laser therapy (LLLT) This treatment has shown potentially promising results, especially if used in combination with ...
In some cases, other medications like spironolactone may be prescribed off-label for hair loss. This is typically only used in women and not in men, because in men it can lead to gynecomastia ...
Spironolactone: Spironolactone is used to treat high blood pressure but is also prescribed off-label for treating acne in women. Spironolactone reduces the amount of androgen hormones in your body ...
However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%
Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.
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