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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
During a digital rectal examination (DRE), a healthcare provider slides a gloved finger into the rectum and presses on the prostate, to check its size and to detect any lumps on the accessible side. If the examination suggests anomalies, a PSA test is performed. If an elevated PSA level is found, a follow-up test is then performed. [2]
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.Abnormal growth of prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels.
PAP immunohistochemical staining is often used with PSA (staining), by pathologists, to help distinguish poorly differentiated carcinomas.For example, poorly differentiated prostate adenocarcinoma (prostate cancer) and urothelial carcinoma (bladder cancer) may appear similar under the microscope, but PAP and PSA staining can help differentiate them; [7] prostate adenocarcinoma often stains ...
Signs and symptoms of pregnancy are common, benign conditions that result from the changes to the body that occur during pregnancy. Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications ...
PSA: prostate-specific antigen: PBSO: partial small bowel obstruction PSC: primary sclerosing cholangitis: PSCH: preoperative systemic chemotherapy PSGN: poststreptococcal glomerulonephritis: PSH: Paroxysmal sympathetic hyperactivity Past surgical history psychosocial history Past medical history (see also medical history) PSI: Pneumonia ...
Serious side effects may include low blood pressure with standing and depression. [ 6 ] [ 7 ] Prazosin is a non-selective inverse agonist of the α 1 -adrenergic receptors . [ 6 ] It works to decrease blood pressure by dilating blood vessels and helps with an enlarged prostate by relaxing the outflow of the bladder . [ 6 ]
There are no drug-related side effects to fertility awareness. [37] FA can be free or have a very low up-front cost. Users may employ a coach, use computer software, or buy a chart, calendar, or basal thermometer. The direct costs are low when compared to other methods.