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It was first identified in 1966 at the Mayo Clinic, by A.G. Engel, [2] and that same year W.K. Engel and J.S. Resnick noted another case that they elaborated in 1975. [ 3 ] [ 4 ] The diagnosis of the disease rests on subacutely evolving weakness after age 40, normal to low CK level , a myopathic EMG with fibrillations , and often a monoclonal ...
Amplified musculoskeletal pain syndrome (AMPS) is an illness characterized by notable pain intensity without an identifiable physical cause. [1] [6] Characteristic symptoms include skin sensitivity to light touch, also known as allodynia. Associated symptoms may include changes associated with disuse including changes in skin texture, color ...
However, the symptoms vary depending on the severity and cause of the condition. Lighter symptoms include pain or heaviness in the legs, hips, glutes and lower back, post-exercise. [6] [8] Mild to severe symptoms include prolonged constant pain, tiredness and discomfort in the lower half of the body.
Often there are no symptoms. [2] If symptoms do occur these may include swelling and pain behind the knee, or knee stiffness. [1] If the cyst breaks open, pain may significantly increase with swelling of the calf. [1] Rarely complications such as deep vein thrombosis, peripheral neuropathy, ischemia, or compartment syndrome may occur. [2] [3]
Intermittent claudication is a symptom and is by definition diagnosed by a patient reporting a history of leg pain with walking relieved by rest. However, as other conditions such as sciatica can mimic intermittent claudication, testing is often performed to confirm the diagnosis of peripheral artery disease. [citation needed]
Prodromal symptoms are typically fever, cough, and rhinorrhea. BACM symptoms that follow are most frequently calf pain, gait complaints, and inability to walk. [2] The condition is self-limited and full restitution can be expected. In very rare cases, however, rhabdomyolysis may develop. [1]
The pain is usually located in the calf muscles of the affected leg and is relieved by rest. [30] This occurs because during exercise, the muscles require more oxygen . Normally, the arteries would be able to increase the amount of blood flow and therefore increase the amount of oxygen going to the exercised muscle.
Symptoms: Fat deposits/swelling in legs and arms not in hands or feet; hands and feet may be affected as the disease progresses. Fat deposits / swelling widespread in legs/arms/torso: Fat deposits/swelling in one limb including hands and feet: Fat deposits widespread Swelling near ankles; brownish discoloration of lower legs (hemosiderin deposits).