Ads
related to: hcv polymerase inhibitors for diabetes mellitus list chart pdf- Download Brochures
Download The Patient Brochure
Educational Resource Hub
- Education Resource Hub
Support Whenever You Need It
Download Brochures & How-To Guides
- Quick Tips & How-To's
Free Diabetes Patient Support
Tips For Living With Diabetes
- Free Diabetes Care App
Download BD™ Diabetes Care App
On Apple Store & Google Play
- Download Brochures
Search results
Results From The WOW.Com Content Network
The non-nucleoside analogue inhibitors inhibit the polymerase activity in different ways, which depend on the allosteric site to which the inhibitor binds. [15] [16] In contrast to the nucleoside inhibitors, non-nucleoside analogue inhibitors do not compete with nucleotides nor the RNA template. Instead, by binding to RNA-dependent RNA ...
HCV genome. Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). [1] It is an RNA-dependent RNA polymerase, having the key function of replicating HCV's viral RNA by using the viral positive RNA strand as a template to catalyze the polymerization of ribonucleoside triphosphates (rNTP) during RNA replication.
Ribonucleotide reductase and DNA polymerase inhibitor. [11] Acute lymphoblastic leukaemia and acute myeloid leukaemia: Myelosuppression, hypokalaemia, cytokine release syndrome, Stevens–Johnson syndrome (uncommon), toxic epidermal necrolysis (uncommon) and pancreatitis (uncommon) Cytarabine: SC, IM, IV, IT: DNA polymerase inhibitor, S-phase ...
HCV is a positive-sense single-stranded RNA virus that has been demonstrated to replicate in the hepatocytes of both humans and chimpanzees. A single HCV polyprotein is translated, and then cleaved by cellular and viral proteases into three structural proteins (core, E1, and E2) and seven nonstructural proteins (p7, NS2, NS3, NS4A, NS4B, NS5A, and NS5B).
Download as PDF; Printable version; ... RNA polymerase inhibitors (2 C, 5 P) S. ... Transferase inhibitors (13 C, 6 P) Pages in category "Enzyme inhibitors"
HCV, as with most RNA viruses, exists as a viral quasispecies, making it very difficult to isolate a single strain or receptor type for study. [64] [65] Current research is focused on small-molecule inhibitors of the viral protease, RNA polymerase and other nonstructural genes.