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Prostate cancer kills around 35,000 men yearly, and about 220,000 men are diagnosed with prostate cancer per year, in North America alone. [104] Prostate cancer is the second leading cause of cancer-caused fatalities in men, and within a man's lifetime, one in six men will have the disease. [ 104 ]
Otto Warburg postulated this change in metabolism is the fundamental cause of cancer, [8] a claim now known as the Warburg hypothesis. Today, mutations in oncogenes and tumor suppressor genes are thought to be responsible for malignant transformation, and the Warburg effect is considered to be a result of these mutations rather than a cause. [9 ...
Palliative care for advanced-stage prostate cancer focuses on extending life and relieving the symptoms of metastatic disease. As noted above, abiraterone is showing some promise in treating advanced-stage prostate cancer. It causes a dramatic reduction in PSA levels and tumor sizes in aggressive advanced-stage prostate cancer for 70% of patients.
“Prostate cancer is smart—it learns to grow despite this hormone therapy” by tapping into testosterone from other sources in the body. ... Chemo can cause side effects like hair loss, nausea ...
This prostate cancer cell death provides a more definitive resolution of the disease than current treatments, such as radiation, that force prostate cancer into dormancy, from which it may at some ...
Prostate cancer is the most diagnosed cancer in men in over half of the world's countries, and the leading cause of cancer death in men in around a quarter of countries. [92] Prostate cancer is rare in those under 40 years old, [93] and most cases occur in those over 60 years, [2] with the average person diagnosed at 67. [94]