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In most of those cases, people had long been told they were allergic to penicillin — usually after developing a rash within several days of taking the antibiotic as a baby or toddler.
Amoxicillin is an antibiotic medication belonging to the aminopenicillin class of the penicillin family. The drug is used to treat bacterial infections [9] such as middle ear infection, strep throat, pneumonia, skin infections, odontogenic infections, and urinary tract infections. [9]
In addition, penicillin is available in different forms. There are different penicillin medications (penicillin G benzathine, penicillin G potassium, Penicillin G sodium, penicillin G procaine, and penicillin V) [3] as well as a number of β-lactam antibiotics derived from penicillin (e.g. amoxicillin).
The most common type of eruption is a morbilliform (resembling measles) or erythematous rash (approximately 90% of cases). [7] Less commonly, the appearance may also be urticarial, papulosquamous, pustular, purpuric, bullous (with blisters) or lichenoid. [3] Angioedema can also be drug-induced (most notably, by angiotensin converting enzyme ...
The organism was first cultured in 1883 by the German surgeon Friedrich Fehleisen from erysipelas lesions. [56] Also in 1884, the German physician Friedrich Loeffler was the first to show the presence of streptococci in the throats of people with scarlet fever. Because not all people with pharyngeal streptococci developed scarlet fever, these ...
The term "toxic shock syndrome" was first used in 1978 by a Denver pediatrician, James K. Todd, to describe the staphylococcal illness in three boys and four girls aged 8–17 years. [28] Even though S. aureus was isolated from mucosal sites in the patients, bacteria could not be isolated from the blood, cerebrospinal fluid, or urine, raising ...
The reaction generally includes a constellation of fever; urticarial polycyclic wheals (a rash that can look similar to hives with small swellings that overlap each other [2]) with central clearing on the trunk, extremities, face, and lateral borders of the hands and feet; oral edema without mucosal involvement; lymphadenopathy; arthralgias; myalgias; and mild proteinuria.
Of course this supposes that someone reporting an allergy really has had an allergic reaction to the drug - the rash could have been from the disease itself (i.e. is a rash that develops with a sore throat promptly treated with a penicillin from the drug, or was the rash about to appear anyway as part of the disease i.e. scarlet fever). Also ...