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Menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the ...
The follicular phase (or proliferative phase) is the phase of the menstrual cycle during which the ovarian follicles mature. The follicular phase lasts from the beginning of menstruation to the start of ovulation. [12] [13] For ovulation to be successful, the ovum must be supported by the corona radiata and cumulus oophorous granulosa cells. [14]
Figure 2. Follicular phase diagram of hormones and their origins. Follicle-stimulating hormone (FSH) is secreted by the anterior pituitary gland (Figure 2). FSH secretion begins to rise in the last few days of the previous menstrual cycle, [3] and is the highest and most important during the first week of the follicular phase [4] (Figure 1).
Because primordial follicles can be dormant for up to 50 years in humans, the length of the ovarian cycle does not include this time. The supply of follicles decreases slightly before birth, and to 500,000 by puberty for the average case (populations at puberty range from 25,000 to 1.5 million). [ 4 ]
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The ovarian reserve and fertility perform optimally around 20–30 years of age. [18] Around 45 years of age, the menstrual cycle begins to change and the follicle pool decreases significantly. [18] The events that lead to ovarian aging remain unclear. The variability of aging could include environmental factors, lifestyle habits or genetic ...
Diagram illustrating how the uterus lining builds up and breaks down during the menstrual cycle Menstruation (also known as a period, among other colloquial terms) is the regular discharge of blood and mucosal tissue from the inner lining of the uterus through the vagina. The menstrual cycle is characterized by the rise and fall of hormones. Menstruation is triggered by falling progesterone ...
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