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Fluoride toxicity is a condition in which there are elevated levels of the fluoride ion in the body. Although fluoride is safe for dental health at low concentrations, [ 1 ] sustained consumption of large amounts of soluble fluoride salts is dangerous.
Antifluoridationist literature links fluoride exposure to a wide variety of effects, including AIDS, allergy, Alzheimer's disease, arthritis, cancer, and low IQ, along with diseases of the gastrointestinal tract, kidney, pineal gland, and thyroid, though there is no scientific evidence linking fluoridation to these adverse health effects. [70] [71]
The pineal gland is present in almost all vertebrates, but is absent in protochordates in which there is a simple pineal homologue. The hagfish , archaic vertebrates, lack a pineal gland. [ 7 ] In some species of amphibians and reptiles, the gland is linked to a light-sensing organ, variously called the parietal eye , the pineal eye or the ...
The fluoride ion is readily absorbed by the stomach and intestines. Ingested fluoride forms hydrofluoric acid in the stomach. In this form, fluoride crosses cell membranes and then binds with calcium and interferes with various enzymes. Fluoride is excreted through urine. Fluoride exposure limits are based on urine testing, which is used to ...
Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea. [3] Fluoride can also damage the parathyroid glands, leading to hyperparathyroidism, the uncontrolled secretion of parathyroid hormones. These hormones regulate calcium concentration in the body.
In the mid Fifties, Waldbott began conducting research in fluoride toxicity, becoming one of the first physicians to warn against what he believed was adverse health effects of water fluoridation, particularly among patients in his allergy practice he considered "hypersensitive" to fluoride. [8]
Kids whose mothers had higher levels of fluoride in their urine were 83% more likely to exhibit a range of neurobehavioral issues, including anxiety, emotional reactivity and physical complaints ...
Also, although fluoride affects the physiology of dental bacteria, [90] its effect on bacterial growth does not seem to be relevant to cavity prevention. [91] Fluoride's effects depend on the total daily intake of fluoride from all sources. [13] About 70–90% of ingested fluoride is absorbed into the blood, where it distributes throughout the ...