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Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
Fluconazole is an antifungal medication used for a number of fungal infections. [5] This includes candidiasis , blastomycosis , coccidioidomycosis , cryptococcosis , histoplasmosis , dermatophytosis , and tinea versicolor . [ 5 ]
A one-time dose of fluconazole by mouth is 90% effective in treating a vaginal yeast infection. [70] For severe nonrecurring cases, several doses of fluconazole is recommended. [20] Local treatment may include vaginal suppositories or medicated douches. Other types of yeast infections require different dosing.
A 2023 study that got a lot of buzz estimated that E.coli-contaminated meat leads to nearly half a million UTIs in the U.S. each year, making it one of the most common causes of UTIs.
Amphotericin B deoxycholate is the most common treatment antifungal agent used to treat Candida infections. [4] Topical antifungal agents are commonly taken in 3 forms: oral suspension, ointment and powder. [4] Oral suspension is mainly used to treat thrush whereas ointment is directly applied onto the infected section. [4]
Many isolates of C. dubliniensis are sensitive to fluconazole.In one study, sixteen of twenty isolates were sensitive to fluconazole, while four were resistant. [5] It has been hypothesized that C. dubliniensis possesses the ability to rapidly develop resistance to fluconazole, especially in patients on long-term therapy.