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Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. [9] Haloperidol is used in the treatment of schizophrenia , tics in Tourette syndrome , mania in bipolar disorder , delirium , agitation, acute psychosis , and hallucinations from alcohol withdrawal .
HPP + is structurally related to the selective dopaminergic neurotoxin MPTP (and its active metabolite MPP +), which induces Parkinson's disease-like symptoms in humans. [ 1 ] [ 2 ] HPP + is a neurotoxin specifically affecting serotonergic and dopaminergic neurons , and its neurotoxicity resembles that of MPTP.
Download as PDF; Printable version; In other projects Wikidata item; ... is a fixed-dose combination medication used for the treatment of Parkinson's disease. [2] [5] ...
In the management of Parkinson's disease, due to the chronic nature of Parkinson's disease (PD), a broad-based program is needed that includes patient and family education, support-group services, general wellness maintenance, exercise, and nutrition. At present, no cure for the disease is known, but medications or surgery can provide relief ...
Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [ 6 ] [ 7 ] [ 9 ] Its elimination half-life after multiple doses is 21 days.
Pseudoparkinsonism, symptoms that are similar to what people with Parkinson's disease experience, including tremulousness and drooling; Hyperprolactinaemia (rare for those treated with clozapine, quetiapine and aripiprazole [18] [38]), which can cause: Galactorrhoea, the unusual secretion of breast milk. Gynaecomastia, abnormal growth of breast ...
The risk of developing tardive dyskinesia after chronic typical antipsychotic usage varies on several factors, such as age and gender, as well as the specific antipsychotic used. The commonly reported incidence of TD among younger patients is about 5% per year. Among older patients incidence rates as high as 20% per year have been reported.
Use of high-potency antipsychotics, a rapid increase in the dosage of antipsychotics, use of long-acting forms of antipsychotics (such as haloperidol) or injectable formulations, or using multiple antipsychotics are all known to increase the risk of developing NMS. [20] [21] [7] Dehydration is a risk factor for the development of NMS. [7]