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The free radical theory of aging states that organisms age because cells accumulate free radical damage over time. [1] A free radical is any atom or molecule that has a single unpaired electron in an outer shell. [2] While a few free radicals such as melanin are not chemically reactive, most biologically relevant free radicals are highly ...
Upon contact with the skin, benzoyl peroxide breaks down, producing oxygen gas, among other things. The oxygen gas is absorbed into the pores of the skin, where it kills off the acne-causing bacterium Cutibacterium acnes. In addition, the free radicals produced can break down dead skin cells.
The classic free-radical syndrome, the iron-storage disease hemochromatosis, is typically associated with a constellation of free-radical-related symptoms including movement disorder, psychosis, skin pigmentary melanin abnormalities, deafness, arthritis, and diabetes mellitus.
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
This earlier study also found that dihydroxyacetone also has an effect on the amino acids and nucleic acids which is bad for the skin. [27] The free radicals are due to the action of UV light on AGE (advanced glycation end-products) as a result of the reaction of DHA with the skin, and the intermediates, such as Amadori products (a type of AGE ...
Octocrylene can penetrate into the skin where it acts as a photosensitizer, resulting in an increased production of free radicals under illumination. [2] It may also pass through the skin, into the blood stream, eventually being metabolized and excreted in urine in form of its metabolites.
[5] It accumulates in the body because of liver damage, reacts with UV light on the skin, and leads to free radical formation. These free radicals damage the skin, leading to ulceration, necrosis, and sloughing. Non-pigmented skin is most commonly affected.
Photoaging or photoageing [1] (also known as "dermatoheliosis" [2]) is a term used for the characteristic changes to skin induced by chronic UVA and UVB exposure. [ 3 ] : 29 Tretinoin is the best studied retinoid in the treatment of photoaging.