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Visual inspection involves the application of ascetic acid or lugol's iodine solution to the cervix. These solutions highlight abnormal areas for easier identification with the naked eye. A magnifying camera called a colposcope can also be utilized for clearer viewing when available. [2]
Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water. [8] Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the ...
The image on the right stains with Lugol's iodine, and identifies a squamous cell carcinoma, which does not pick up the stain. Chromoendoscopy is a medical procedure wherein dyes (often the same stains used in histology ) are instilled into the gastrointestinal tract at the time of visualization with fibre-optic endoscopy .
This is often done through colposcopy, a magnified visual inspection of the cervix aided by using a dilute acetic acid (e.g. vinegar) solution to highlight abnormal cells on the surface of the cervix, [5] with visual contrast provided by staining the normal tissues a mahogany brown with Lugol's iodine. [59]
The technique, termed VIA (Visual Inspection with Acetic Acid)/Cryo, was endorsed by the World Health Organization in 2010. Vinegar is brushed on a woman's cervix and precancerous spots turn white. These can be instantly frozen off with a metallic probe cooled with dry ice.
Lugol's solution or Lugol's iodine (IKI) is a brown solution that turns black in the presence of starches and can be used as a cell stain, making the cell nuclei more visible. Used with common vinegar (acetic acid), Lugol's solution is used to identify pre-cancerous and cancerous changes in cervical and vaginal tissues during "Pap smear" follow ...
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