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  2. Translation regulation by 5′ transcript leader cis-elements

    en.wikipedia.org/wiki/Translation_regulation_by_5...

    Alterations in translation of mRNA into proteins rapidly modulates the proteome without changing upstream steps such as transcription, pre-mRNA splicing, and nuclear export. [1] The strict regulation of translation in both space and time is in part governed by cis-regulatory elements located in 5′ mRNA transcript leaders (TLs) and 3 ...

  3. Transcription error - Wikipedia

    en.wikipedia.org/wiki/Transcription_error

    Transcription and transposition errors are found everywhere, even in professional articles in newspapers or books. They can be missed by editors quite easily, just as they can be created quite easily. The most obvious cure for the errors is for the user to watch the screen when they type, and to proofread.

  4. ncRNA therapy - Wikipedia

    en.wikipedia.org/wiki/NcRNA_therapy

    One of the major issues that hinders the ncRNA therapy is the stability of the single stranded RNA molecule. RNA is typically single stranded therefore slightly unstable as compared to dsDNA molecules. This however can be overcome by fabricating the single stranded RNA to double stranded RNA(dsRNA).

  5. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    Several cell function specific transcription factor proteins (in 2018 Lambert et al. indicated there were about 1,600 transcription factors in a human cell [41]) generally bind to specific motifs on an enhancer [22] and a small combination of these enhancer-bound transcription factors, when brought close to a promoter by a DNA loop, govern the ...

  6. Termination signal - Wikipedia

    en.wikipedia.org/wiki/Termination_signal

    Termination of transcription occurs due to termination signal. In molecular biology , a termination signal is a sequence that signals the end of transcription or translation . [ 1 ] Termination signals are found at the end of the part of the chromosome being transcribed during transcription of mRNA .

  7. Attenuator (genetics) - Wikipedia

    en.wikipedia.org/wiki/Attenuator_(genetics)

    Depending on the metabolic conditions, the attenuator either stops transcription at that point or allows read-through to the structural gene part of the mRNA and synthesis of the appropriate protein. Attenuation is a regulatory feature found throughout Archaea and Bacteria causing premature termination of transcription . [ 2 ]