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American evidence-based clinical guidelines were published in 2016 for the treatment of VTE. [42] In the UK, guidelines by the National Institute for Health and Care Excellence (NICE) were published in 2012, updated in 2020. [43] These guidelines do not cover rare forms of thrombosis, for which an individualized approach is often needed. [5]
VTE rarely occurs in children, but when it does, it predominantly affects hospitalized children. [170] Children in North America and the Netherlands have VTE rates that range from 0.07 to 0.49 out of 10,000 children annually. [170] Meanwhile, almost 1% of those aged 85 and above experience VTE each year. [3]
If the patient is 'low risk' using the CHA 2 DS 2-VASc score (that is, 0 in males or 1 in females), no anticoagulant therapy is recommended. In males with 1 stroke risk factor (that is, a CHA 2 DS 2-VASc score=1), antithrombotic therapy with OAC may be considered, and people's values and preferences should be considered. [24]
It has been developed to guide decision-making in chronic venous insufficiency evaluation and treatment. [6] The CEAP classification for CVI is as follows: [citation needed] Clinical C0: no obvious feature of venous disease; C1: the presence of reticular or spider veins; C2: Obvious varicose veins; C3: Presence of edema but no skin changes
This evidence convinced most physicians who specialize in diabetes care that an important goal of treatment is to make the biochemical profile of the diabetic patient (blood lipids, HbA1c, etc.) as close to the values of non-diabetic people as possible. This is especially true for young patients with many decades of life ahead.
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