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The fact that oxygen changes the radiation chemistry might be one reason why oxygenated tissues are more sensitive to irradiation than the deoxygenated tissue at the center of a tumor. The free radicals, such as the hydroxyl radical, chemically modify biomolecules such as DNA, leading to damage such as breaks in the DNA strands. Some substances ...
The hydroxyl radical, Lewis structure shown, contains one unpaired electron. Lewis dot structure of a Hydroxide ion compared to a hydroxyl radical. In chemistry, a radical, also known as a free radical, is an atom, molecule, or ion that has at least one unpaired valence electron.
The hydroxyl radical can damage virtually all types of macromolecules: carbohydrates, nucleic acids , lipids (lipid peroxidation) and amino acids (e.g. conversion of Phe to m-Tyrosine and o-Tyrosine). The hydroxyl radical has a very short in vivo half-life of approximately 10 −9 seconds and a high reactivity. [5]
Such states of matter are studied in condensed matter physics. In extreme conditions found in some stars and in the early universe, atoms break into their constituents and matter exists as some form of degenerate matter or quark matter. Such states of matter are studied in high-energy physics.
Atoms that possess too few bonding partners to satisfy their valences and that possess unpaired electrons are termed "free radicals"; so, often, are molecules containing such atoms. When a free radical exists in an immobilized environment (for example, a solid), it is referred to as an "immobilized free radical" or a "dangling bond".
Fully 70% of the matter density in the universe appears to be in the form of dark energy. Twenty-six percent is dark matter. Only 4% is ordinary matter. So less than 1 part in 20 is made out of matter we have observed experimentally or described in the standard model of particle physics. Of the other 96%, apart from the properties just ...
Radiation used for cancer treatment is called ionizing radiation because it forms ions in the cells of the tissues it passes through as it dislodges electrons from atoms. This can kill cells or change genes so the cells cannot grow. Other forms of radiation such as radio waves, microwaves, and light waves are called non-ionizing.
Chemistry is the scientific study of the properties and behavior of matter. [1] It is a physical science within the natural sciences that studies the chemical elements that make up matter and compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during reactions with other substances.