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A chromophobe is a histological structure that does not stain readily, and thus appears relatively pale under the microscope.. Chromophobe cells are one of three cell stain types present in the anterior and intermediate lobes of the pituitary gland, the others being basophils and acidophils.
The anterior pituitary (also called the adenohypophysis or pars anterior) is a major organ of the endocrine system.The anterior pituitary is the glandular, anterior lobe that together with the (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis) which, in humans, is located at the base of the brain, protruding off the bottom of the hypothalamus.
The anterior lobe of the pituitary can be divided into the pars tuberalis (pars infundibularis) and pars distalis (pars glandularis) that constitutes ~80% of the gland. The pars intermedia (the intermediate lobe) lies between the pars distalis and the pars tuberalis, and is rudimentary in the human, although in other species it is more ...
In the anterior pituitary, the term "acidophil" is used to describe two different types of cells which stain well with acidic dyes.. somatotrophs, which secrete growth hormone (a peptide hormone)
Rinehart and Farquhar first discovered FS cells through electron microscopy of the anterior pituitary gland. Vila-Porcile named these non-endocrine cells "folliculo-stellate" cells in 1972 due to their stellate (star) shape, and their location lining the lumen of small follicules in the anterior pituitary. [1]
Rathke's pouch is a sac-like structure that gives rise to the pars distalis, pars intermedia, and pars tuberalis of the pituitary gland. The cells of Rathke's pouch proliferate and differentiate into various hormone-producing cells, including Somatotrophs, Lactotrophs, Corticotrophs, Thyrotrophs, and Gonadotrophs.
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An anterior pituitary basophil is a type of cell in the anterior pituitary which manufactures hormones.. It is called a basophil because it is basophilic (readily takes up bases), and typically stains a relatively deep blue or purple.