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  2. Treatment of bipolar disorder - Wikipedia

    en.wikipedia.org/wiki/Treatment_of_bipolar_disorder

    In light of recent evidence, olanzapine (Zyprexa) has been FDA approved as an effective monotherapy for the maintenance of bipolar disorder. [22] A head-to-head randomized control trial in 2005 has also shown olanzapine monotherapy to be just as effective and safe as lithium in prophylaxis. [23]

  3. Mood stabilizer - Wikipedia

    en.wikipedia.org/wiki/Mood_stabilizer

    FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition. [10] Carbamazepine

  4. Lamotrigine - Wikipedia

    en.wikipedia.org/wiki/Lamotrigine

    June 2003 — approved for maintenance treatment of bipolar II disorder; the first such medication since lithium. [citation needed] January 2004 — for use as monotherapy for the treatment of partial seizures in adult patients when converting from the anti-epileptic drug valproate (including valproic acid) [citation needed]

  5. Electronic common technical document - Wikipedia

    en.wikipedia.org/wiki/Electronic_Common...

    On May 5, 2015, the U.S. Food & Drug Administration published a final, binding guidance document [7] requiring certain submissions in electronic (eCTD) format within 24 months. The projected date for mandatory electronic submissions is May 5, 2017 for New Drug Applications (NDAs), Biologic License Applications (BLAs), Abbreviated New Drug ...

  6. CFR - Code of Federal Regulations Title 21

    highline.huffingtonpost.com/miracleindustry/...

    PART 314 ­­ APPLICATIONS FOR FDA APPROVAL TO MARKET A NEW DRUG Subpart B­­Applications Sec. 314.50 Content and format of an application. Applications and supplements to approved applications are required to be submitted in the form and contain the information, as appropriate

  7. Lithium (medication) - Wikipedia

    en.wikipedia.org/wiki/Lithium_(medication)

    In 1970, lithium was approved by the United States Food and Drug Administration (FDA) for the treatment of bipolar disorder, which remains its primary use in the US. [ 5 ] [ 17 ] It is sometimes used when other treatments are not effective in a number of other conditions, including major depression , [ 18 ] schizophrenia , disorders of impulse ...

  8. Lurasidone - Wikipedia

    en.wikipedia.org/wiki/Lurasidone

    Lurasidone was first approved for medical use in the United States in 2010. [2] In 2013, it was approved in Canada and by the U.S. Food and Drug Administration (FDA) to treat bipolar depression, either as monotherapy or adjunctively with lithium or valproate.

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    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!