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Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
This list may not reflect recent changes. * Antidiarrheal; A. Albumin tannate; Template:Antidiarrheals, intestinal anti-inflammatory and anti-infective agents;
Drugs such as morphine or codeine can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is loperamide which is only an agonist of the μ opioid receptors in the large intestine and does not have opioid affects in the central nervous system as it doesn't cross the blood–brain barrier in significant ...
Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QA07. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
Crofelemer (USAN, trade name Mytesi) is an antidiarrheal indicated for the symptomatic relief of non-infectious diarrhea in adult patients with HIV/AIDS on antiretroviral therapy. [1] Other possible uses include diarrhea in children, acute infectious diarrhea , and diarrhea in patients with irritable bowel syndrome . [ 2 ]
Loperamide can decrease the absorption of some other drugs. As an example, saquinavir concentrations can decrease by half when given with loperamide. [19] Loperamide is an antidiarrheal agent, which decreases intestinal movement. As such, when combined with other antimotility drugs, the risk of constipation is increased.
An antipropulsive is a drug used in the treatment of diarrhea. It does not address the underlying cause (for example, infection or malabsorption), but it does decrease motility. Examples include diphenoxylate, loperamide, and eluxadoline.
It can cause a black tongue and black stools in some users of the drug when it combines with trace amounts of sulfur in saliva and the colon to form bismuth sulfide. [7] Bismuth sulfide is a highly insoluble black salt, and the discoloration seen is temporary and harmless. Long-term use (more than six weeks) may lead to accumulation and ...