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The central nervous system (CNS) is derived from the ectoderm—the outermost tissue layer of the embryo. In the third week of human embryonic development the neuroectoderm appears and forms the neural plate along the dorsal side of the embryo. The neural plate is the source of the majority of neurons and glial cells of the CNS.
Human embryonic development or human embryogenesis is the development and formation of the human embryo.It is characterised by the processes of cell division and cellular differentiation of the embryo that occurs during the early stages of development.
Embryonic age: Week nr 5. 4 weeks old. 29–35 days from fertilization. The embryo measures 8 mm (0.31 in) in length and weighs about 1 gram. [4] Optic vesicles and optic cups form the start of the developing eye. Nasal pits form. The brain divides into 5 vesicles, including the early telencephalon. Leg buds form and hands form as flat paddles ...
Three flexures form in the part of the embryonic neural tube that develops into the brain. At four weeks gestational age in the human embryo, the neural tube has developed at the cranial end into three swellings – the primary brain vesicles. The space into which the cranial part of the neural tube is developing is limited.
It is hypothesized in [66] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
In embryology, Carnegie stages are a standardized system of 23 stages used to provide a unified developmental chronology of the vertebrate embryo.. The stages are delineated through the development of structures, not by size or the number of days of development, and so the chronology can vary between species, and to a certain extent between embryos.
Stages of neuronal development in the fetal cerebral cortex Model of mammalian neurogenesis [4]. During embryonic development, the mammalian central nervous system (CNS; brain and spinal cord) is derived from the neural tube, which contains NSCs that will later generate neurons. [3]
Cortical white matter increases from childhood (~9 years) to adolescence (~14 years), most notably in the frontal and parietal cortices. [8] Cortical grey matter development peaks at ~12 years of age in the frontal and parietal cortices, and 14–16 years in the temporal lobes (with the superior temporal cortex being last to mature), peaking at about roughly the same age in both sexes ...