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Treatment of paucibacillary leprosy is with the medications dapsone, rifampicin, and clofazimine for six months. [9] Treatment for multibacillary leprosy uses the same medications for 12 months. [9] A number of other antibiotics may also be used. [3] These treatments are provided free of charge by the World Health Organization. [4]
They concluded that a single dose of a combination of rifampicin, ofloxacin and minocycline is an acceptable and cost-effective alternative regimen for the treatment of single-lesion paucibacillary leprosy and the duration of the standard regimen for multibacillary leprosy could be shortened to 12 months.
The small brick-red rod-shaped cells appear in clusters. Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
A leprostatic agent is a drug that interferes with proliferation of the bacterium that causes leprosy. [1][2] The following agents are leprostatic agents: [3] Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Host defenses are crucial in determining the patient's response to the disease, the clinical presentation, and the ...
Aldo Castellani was the first to prepare a substance similar to lepromin while attempting to produce a leprosy vaccine. [6] [7] Kensuke Mitsuda worked with lepromin starting in 1916 and published the first paper on it in 1919 [8] However, he retained Ernest Reinhold Rost's earlier name leprolin and his original idea was to find a test that distinguishes leprosy patients from non-leprosy persons.
The most common drugs to treat leprosy include rifampicin and clofazimine in combination with dapsone for multibacillary leprosy. A single dose of antimicrobial combination to cure single lesion paucibacillary leprosy comprises ofloxacin, rifampicin, and minocycline. Praziquantel can be useful for treating infections caused by all Schistosoma ...