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Indapamide is a thiazide-like ... blockers and lesser prevalence of side-effects when compared to ACE ... reduced all cause mortality in young-elderly patients with a ...
Side effects [ edit ] Additionally, cramps , low blood pressure , allergic reactions , skin rashes , gastrointestinal disorders , dry cough , erectile dysfunctions , dry mouth , and a risk of dehydration in the elderly and in people who have congestive heart failure .
The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.
Confusion sometimes occurs because thiazide-like diuretics such as indapamide are referred to as thiazides despite not having the thiazide chemical structure. [6] When used this way, "thiazide" refers to a drug which acts at the thiazide receptor. [7]
The Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BLA) was a 2005 landmark trial that compared the effects of the established therapy of the combination of atenolol and bendroflumethiazide to the new drug combination of amlodipine and perindopril (trade names Viacoram, AceryCal etc.). [12]
Increased urination is a commonly reported side effect, particularly during the initial phase following treatment initiation; this is mostly transient and tends to reduce with sustained treatment. Common side effects for antimineralocorticoid medications include nausea and vomiting, stomach cramps and diarrhoea. [4]
Common side effects include headaches, dizziness, fatigue, and cough. [1] Serious side effects may include liver problems, angioedema, kidney problems, and high blood potassium. [1] Use in pregnancy and breastfeeding is not recommended. [5] It is an ACE inhibitor and works by decreasing renin-angiotensin-aldosterone system activity. [1]
Moexipril is generally well tolerated in elderly patients with hypertension. [6] Hypotension, dizziness, increased cough, diarrhea, flu syndrome, fatigue, and flushing have been found to affect less than 6% of patients who were prescribed moexipril.