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A cramp is a sudden, involuntary, painful skeletal muscle contraction [1] [2] or overshortening associated with electrical activity; [3] while generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the affected muscle.
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
“These cramps are usually felt in the lower pelvis, vagina, or even rectal area,” explains Alyssa Dweck, M.D., OB-GYN, author of The Complete A to Z for Your V, and sexual reproductive health ...
The symptoms (and their severity) experienced by women with PGP vary, but include: Present swelling and/or inflammation over joint. Difficulty lifting leg. Pain pulling legs apart. Inability to stand on one leg. Inability to transfer weight through pelvis and legs. Pain in hips and/or restriction of hip movement. Transferred nerve pain down leg.
Muscle stiffness may also be present; if muscle weakness is not also present, and cramps are more severe, the stiffness may be categorized instead as cramp fasciculation syndrome. [3] Cramp fasciculation is a variant of BFS which presents with muscle pain and exercise intolerance. [2] [4]
The distal veins are removed following the complete ablation of the proximal vein. This treatment is most commonly used for varicose veins off of the great saphenous vein, small saphenous vein, and pudendal veins. [60] Follow-up treatment to smaller branch varicose veins is often needed in the weeks or months after the initial procedure.