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The Starling principle holds that fluid movement across a semi-permeable blood vessel such as a capillary or small venule is determined by the hydrostatic pressures and colloid osmotic pressures (oncotic pressure) on either side of a semipermeable barrier that sieves the filtrate, retarding larger molecules such as proteins from leaving the blood stream.
Oncotic pressure, or colloid osmotic-pressure, is a type of osmotic pressure induced by the plasma proteins, notably albumin, [1] in a blood vessel's plasma (or any other body fluid such as blood and lymph) that causes a pull on fluid back into the capillary.
In fluid statics, capillary pressure is the pressure between two immiscible fluids in a thin tube (see capillary action), resulting from the interactions of forces between the fluids and solid walls of the tube. Capillary pressure can serve as both an opposing or driving force for fluid transport and is a significant property for research and ...
In medicine, hydrostatic pressure in blood vessels is the pressure of the blood against the wall. It is the opposing force to oncotic pressure. In capillaries, hydrostatic pressure (also known as capillary blood pressure) is higher than the opposing “colloid osmotic pressure” in blood—a “constant” pressure primarily produced by ...
Capillary hydrostatic pressure P c = 0.2 × Arterial Pressure + Venous Pressure 1.2 25mmHg (arteriolar end) 10mmHg (venous end) P i: Tissue interstitial pressure Determined by the compliance of tissue Compliance = volume/Δ pressure Varies by location ≅ −6 mmHg Π c: Capillary oncotic pressure Measured across semipermeabel membrane
The relatively uniform pressure in the arteries indicate that these blood vessels act as a pressure reservoir for fluids that are transported within them. Pressure drops gradually as blood flows from the major arteries, through the arterioles, the capillaries until blood is pushed up back into the heart via the venules, the veins through the ...
A capillary is a small blood vessel, from 5 to 10 micrometres in diameter, and is part of the microcirculation system. Capillaries are microvessels and the smallest blood vessels in the body. They are composed of only the tunica intima (the innermost layer of an artery or vein), consisting of a thin wall of simple squamous endothelial cells. [2]
The pressures that favor this movement are blood colloid osmotic pressure (BCOP) and interstitial fluid hydrostatic pressure (IFHP). [11] Whether a substance is filtrated or reabsorbed depends on the net filtration pressure (NFP), which is the difference between hydrostatic (BHP and IFHP) and osmotic pressures (IFOP and BCOP). [ 5 ]