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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
The medical uses of silver include its use in wound dressings, creams, and as an antibiotic coating on medical devices. [2] [3] [4] Wound dressings containing silver sulfadiazine or silver nanomaterials may be used to treat external infections.
Marion Merrell Dow and its predecessor Marion Laboratories was a U.S. pharmaceutical company based in Kansas City, Missouri, from 1950 until 1996.. The company specialized in bringing to market drugs that had been discovered but unmarketed by other companies including Cardizem which treats arrhythmias and high blood pressure, Carafate (an ulcer treatment), Gaviscon (an antacid), Seldane (a ...
'However, these conventional dressings tend to adhere to the wound surface (Thomas 1995) and their need for frequent changes traumatises newly epithelialised surfaces and delays healing. Silver sulphadiazine cream itself is also thought to delay wound healing due to a toxic effect on regenerating keratinocytes (Wasiak 2005)'
Occlusive dressings come in various forms, including petrolatum gauze, which sticks to the skin surrounding the wound using petrolatum. They can also be used to enhance the penetration and absorption of topically-applied medications, such as ointments and creams .
Zam-Buk is a patent medicine which was produced by the Zam-Buk Company of Leeds, England, founded by Charles Edward Fulford.It was first sold by his Bile Beans company in 1902, [1] as a herbal balm and antiseptic ointment; the use of a complementary Zam-Buk soap was recommended to augment the treatment.