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Crystals can also appear as poorly defined aggregates of granular material, termed amorphous urates or amorphous phosphates (urates form in acid urine while phosphates form in alkaline urine). These are of no clinical significance, but they can interfere with microscopy by obscuring other elements (especially bacteria). [ 125 ]
Crystalluria refers to crystals found in the urine when performing a urine test. Crystalluria is considered often as a benign condition and as one of the side effects of sulfonamides and penicillins. The main reason for the identification of urinary crystals is to detect the presence of the relatively few abnormal types that may represent a ...
Struvite crystals in a human urine sample with a pH of 9. Abundant amorphous phosphate crystals, several squamous and non-squamous epithelial cells and a few leukocytes can also be observed. Another image from the same urine sample as with the image on the left.
A large portion of the crystals in a urine sediment will have this type of morphology, as they can grow at any pH and naturally occur in normal urine. Calcium oxalate monohydrate crystals vary in shape, and can be shaped like dumbbells, spindles, ovals, or picket fences, the last of which is most commonly seen due to ethylene glycol poisoning. [12]
Tumor lysis syndrome may lead to acute kidney injury when uric acid crystals are deposited in the kidneys. [41] Treatment includes hyperhydration to dilute and excrete uric acid via urine , rasburicase to reduce levels of poorly soluble uric acid in blood, or allopurinol to inhibit purine catabolism from adding to uric acid levels.
Urine: For cystine crystals, and casts. The most specific test is the cyanide–nitroprusside test; Ultrasound/CT scan to reveal if a stone is present. Genetic analysis to determine which mutation associated with the disease may be present.
The urine test strip test for specific gravity is based on the change in dissociation constant (pK a) of an anionic polyelectrolyte (poly-(methyl vinyl ether/maleic anhydride)) in an alkali medium that is ionised and releases hydrogen ions in proportion to the number of cations present in the solution. [6]
A urine test is any medical test performed on a urine specimen. The analysis of urine is a valuable diagnostic tool because its composition reflects the functioning of many body systems, particularly the kidneys and urinary system , and specimens are easy to obtain. [ 1 ]