Search results
Results From The WOW.Com Content Network
Benzoylecgonine is the main metabolite of cocaine, formed by the liver and excreted in the urine. ... Benzoylecgonine is sometimes found in drinking water supplies.
Benzoylecgonine (197e) is the inactive primary metabolite of cocaine generated through hydrolysis of the C2 methyl ester. In vitro binding studies indicate that benzoylecgonine is ~2,200x less potent than cocaine at the dopamine transporter, possibly due to zwitterion formation preventing strong DAT binding.
Generally speaking benzoylecgonine is eliminated from someone's urine between three and five days. In urine from heavy cocaine users, benzoylecgonine can be detected within four hours after intake and in concentrations greater than 150 ng/mL for up to eight days later. [108]
Cocaethylene (ethylbenzoylecgonine) is the ethyl ester of benzoylecgonine. It is structurally similar to cocaine , which is the methyl ester of benzoylecgonine. Cocaethylene is formed by the liver when cocaine and ethanol coexist in the blood. [ 1 ]
Coca alkaloids are the alkaloids found in the coca plant, Erythroxylum coca. [1] They are predominantly of either the pyrrolidine or the tropane types. Tropane-type alkaloids
Coca is any of the four cultivated plants in the family Erythroxylaceae, native to western South America.Coca is known worldwide for its psychoactive alkaloid, cocaine. ...
All three acetylcholine-inhibiting chemicals can also be found in the leaves, stems, and flowers in varying, unknown amounts in Brugmansia (angel trumpets), a relative of Datura. The same is also true of many other plants belonging to subfamily Solanoideae of the Solanaceae, the alkaloids being concentrated particularly in the leaves and seeds ...
Esterom is an investigational drug being studied as a topical analgesic.Chemically, it is a mixture of compounds derived from the esterification of cocaine in propylene glycol. [1]