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Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
The causes of macular edema are numerous and different causes may be inter-related. It is commonly associated with diabetes.Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.
Retinopathy, or retinal vascular disease, can be broadly categorized into proliferative and non-proliferative types. Frequently, retinopathy is an ocular manifestation of systemic disease as seen in diabetes or hypertension. [3] Diabetes is the most common cause of retinopathy in the U.S. as of 2008. [4]
Dietary antioxidant vitamins, minerals, and carotenoids do not appear to affect the onset; [5] however, dietary supplements may slow the progression in those who already have the disease. [ 5 ] Age-related macular degeneration is a main cause of central blindness among the working-aged population worldwide. [ 6 ]
Cotton wool spots are typically a sign of another disease state, most common of which is diabetic retinopathy. [2] The irregularly shaped white patches are a result of ischemia , or reduced blood flow and oxygen, in the retinal nerve fiber layer , which is located in the distribution of the capillaries of the superficial layer of the retina. [ 2 ]
Intraretinal microvascular abnormalities (IRMA) are abnormalities of the blood vessels that supply the retina of the eye, a sign of diabetic retinopathy. [1] IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA from retinal neovascularization is to perform fluorescein ...