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The Malaria Journal is a peer-reviewed open access medical journal published by BioMed Central. It was established in 2002 [ 1 ] and covers research on malaria and related topics. The editor-in-chief is Marcel Hommel ( University of Liverpool ).
While a series of research publications came out of the Stateville Penitentiary experiments, the results had a minimal long-term impact on malaria treatment methods. The main legacy of the study is instead the ethical contention raised by prisoner experimentation , manifesting in the trials of Nazi Germany for its experiments on human subjects.
In the mid-20th century, P. knowlesi became popular as a tool for studying Plasmodium biology and was used for basic research, vaccine research, and drug development. P. knowlesi is still used as a laboratory model for malaria, as it readily infects the model primate the rhesus macaque, and can be grown in cell culture in human or macaque blood.
The Malaria Eradication Research Agenda (malERA) initiative was a consultative process to identify which areas of research and development (R&D) must be addressed for worldwide eradication of malaria.
The major areas of research carried out over the years are on mosquito fauna surveys, development of genetic and molecular markers for important malaria vectors and parasites, cytotaxonomic studies identifying major vectors as species complexes and laboratory and field studies to examine the biological variations among sibling species ...
Human genetic resistance to malaria refers to inherited changes in the DNA of humans which increase resistance to malaria and result in increased survival of individuals with those genetic changes. The existence of these genotypes is likely due to evolutionary pressure exerted by parasites of the genus Plasmodium which cause malaria.
Plasmodium malariae is a parasitic protozoan that causes malaria in humans. It is one of several species of Plasmodium parasites that infect other organisms as pathogens, also including Plasmodium falciparum and Plasmodium vivax, responsible for most malarial infection.
Worldwide, malaria is a leading cause of premature mortality, particularly in children under the age of five, with an estimated 207 million cases and more than half a million deaths in 2012, according to the World Malaria Report 2013 published by the World Health Organization (WHO). The death toll increased to one million as of 2018 according ...