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The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. [2] It consists of the cerebral peduncles , tegmentum , and tectum . It is functionally associated with vision, hearing, motor control, sleep and wakefulness, arousal ( alertness ), and temperature regulation.
The mesencephalon is the second of the three primary vesicles, and does not further differentiate into a secondary brain vesicle. This will become the midbrain. The third primary vesicle, the rhombencephalon (hindbrain) will further differentiate into two secondary vesicles, the metencephalon and the myelencephalon.
Caudally, it is continuous with the fourth ventricle at the junction of the mesencephalon and pons. [3] The midbrain tegmentum is situated anteriorly to the cerebral aqueduct. [3] The portion of the tegmentum posterior to the aqueduct is the tectum. [1] The superior and inferior colliculi that make up the corpora quadrigemina are situated ...
Out of these neurons, 16 billion (19%) are located in the cerebral cortex, and 69 billion (80%) are in the cerebellum. [3] [41] Types of glial cell are astrocytes (including Bergmann glia), oligodendrocytes, ependymal cells (including tanycytes), radial glial cells, microglia, and a subtype of oligodendrocyte progenitor cells. Astrocytes are ...
Anatomically, as the name suggests, the MLR is located in the mesencephalon (or midbrain), ventral to the inferior colliculus and near the cuneiform nucleus. [6] Although identifying the exact anatomical substrates of the MLR has been subject to considerable debate, the pedunculopontine nucleus (PPN), cuneiform nucleus, and midbrain ...
The midbrain, or mesencephalon, is situated above and rostral to the pons. It includes nuclei linking distinct parts of the motor system, including the cerebellum, the basal ganglia and both cerebral hemispheres, among others. Additionally, parts of the visual and auditory systems are located in the midbrain, including control of automatic eye ...
It is located between the ventricular system and distinctive basal or ventral structures at each level. It forms the floor of the midbrain (mesencephalon) whereas the tectum forms the ceiling. [2] It is a multisynaptic network of neurons that is involved in many subconscious homeostatic and reflexive pathways. It is a motor center that relays ...
One of the most influential early contributions was a 1959 paper titled What the frog's eye tells the frog's brain: the paper examined the visual responses of neurons in the retina and optic tectum of frogs, and came to the conclusion that some neurons in the tectum of the frog are wired to combine elementary responses in a way that makes them ...