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In adults, absolute lymphocytosis is present when the lymphocyte count is greater than 5000 per microliter (5.0 x 10 9 /L), in older children greater than 7000 per microliter and in infants greater than 9000 per microliter. [1] Lymphocytes normally represent 20% to 40% of circulating white blood cells. When the percentage of lymphocytes exceeds ...
This disease is known for an indolent clinical course and incidental discovery. [1] The most common physical finding is moderate splenomegaly. B symptoms are seen in a third of cases, and recurrent infections due to anaemia and/or neutropenia [6] are seen in almost half of cases.
CLL is the most common type of leukemia in the Western world. It most commonly affects individuals over the age of 65, due to the accumulation of genetic mutations that occur over time. [3] [18] CLL is rarely seen in individuals less than 40 years old. [19]
Lymphoma is the most common form of hematological malignancy, or "blood cancer", in the developed world. Taken together, lymphomas represent 5.3% of all cancers (excluding simple basal cell and squamous cell skin cancers) in the United States and 55.6% of all blood cancers.
Acute lymphoblastic leukemia represents approximately 20% of adults and 80% of childhood leukemias, making it the most common childhood cancer. [5] Although 80 to 90% of children will have a long term complete response with treatment, [ 45 ] : 1527 it remains the leading cause of cancer-related deaths among children.
[7] [8] In 2012, it had newly developed in 352,000 people. [10] It is the most common type of cancer in children, with three-quarters of leukemia cases in children being the acute lymphoblastic type. [3] However, over 90% of all leukemias are diagnosed in adults, CLL and AML being most common. [3] [14] It occurs more commonly in the developed ...
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