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A cell strain is derived either from a primary culture or a cell line by the selection or cloning of cells having specific properties or characteristics which must be defined. Cell strains are cells that have been adapted to culture but, unlike cell lines, have a finite division potential.
An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur ...
In a meta-analysis study a line-up style test was used for a child witness to identify a culprit among other suspects. [15] The results show that children over the age of 5 were able to identify a culprit (when the culprit was present) at a comparable rate to adults but children up to age 14 produced far greater number of false identifications ...
Test Norms - Part of the standardization of large-scale tests (see above). Norms help psychologists learn about individual differences. For example, a normed personality scale can help psychologists understand how some people are high in negative affectivity (NA) and others are low or intermediate in NA. With many psychoeducational tests, test ...
There are two principal ways in which a cell line can become contaminated: cell cultures are often exchanged between research groups; if, during handling, a sample is contaminated and then passed on, subsequent exchanges of cells will lead to the contaminating population being established, although parts of the supposed cell line are still genuine.
Currently, there are many concerns within the research community about the validity and purity of cell strains. Contamination has risen within and among laboratories. CPEs can be used to test the purity of a certain cell line. For example, HeLa CCL-2 is a common cell line used in a wide
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A skinpatch test has been designed and is used in Canada to measure development of rashes, inflammation, swelling or abnormal tissue growth on human volunteers. [25] Unlike corrosives, substances defined as irritants cause only reversible skin damage. Another approach has been the development of test methods that use cultured human cells.