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Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [4] It is also used to decrease the risk of heart problems in those at high risk. [4] It is taken by mouth. [4]
10599 28253 Ensembl ENSG00000134538 ENSMUSG00000030236 UniProt Q9Y6L6 Q9JJL3 RefSeq (mRNA) NM_006446 NM_020495 NM_178235 RefSeq (protein) NP_006437 NP_065241 Location (UCSC) Chr 12: 21.13 – 21.24 Mb Chr 6: 141.58 – 141.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 ...
Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
With median follow-up of 6 years, simvastatin+ezetimibe was found to reduce the primary outcome of CV mortality, major CV event, or nonfatal stroke (34.7% vs. 32.7%; P=0.016; NNT 50 per 7 years or NNT 350 per 1 year ). There was no reduction in all-cause or CV mortality with simvastatin+ezetimibe, though there was a reduction in MI and stroke. [6]
Alendronic acid/colecalciferol, sold under the brand name Fosamax Plus D among others, is a medication for the treatment of osteoporosis in men or in postmenopausal women. [ 3 ] [ 2 ] [ 4 ] [ 6 ] Alendronic acid/colecalciferol was approved for use in the United States and in the European Union in 2005.
Lovastatin is a prodrug, an inactive lactone in its native form, the gamma-lactone closed ring form in which it is administered, is hydrolysed in vivo to the β-hydroxy acid open ring form; which is the active form. [citation needed] Lovastatin and other statins have been studied for their chemopreventive and chemotherapeutic effects.
Two compounding pharmacies in Florida are allegedly offering contaminated copycat versions of semaglutide, the drug found in Ozempic and Wegovy, Novo Nordisk said Thursday.
Pitavastatin is indicated for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. [citation needed]A 2009 study of the 104-week LIVES trial found pitavastatin increased HDL cholesterol, especially in patients with HDL lower than 40 mg/dL, who had a 24.6% rise, in addition to reducing LDL cholesterol 31.3%. [5]